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WIN 55,212-2 mesylate

目录号: A11932
CB receptor 激动剂
WIN 55,212-2 是一种强效的大麻素受体激动剂,在大鼠神经病理性疼痛模型中被发现具有强效的镇痛作用。它通过受体介导的信号传导激活 p42p44 MAP 激酶。
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用WIN 55,212-2 mesylate发表的2篇文献
  • Vida mirzaie, .et al. , Research Square, 2024, October
  • Greish K, .et al. , J Control Release, 2018, Dec 10;291:184-195 PMID: 30367922
  • 生物活性
    Discription WIN 55,212-2 is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling.
    产品信息
    目录号 A11932
    分子式 C27H26N2O3.CH3SO3H
    分子量 522.6
    CAS号 131543-23-2
    SMILES CC1=C(C2=C3N1[C@@H](COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65.CS(=O)(=O)O
    其他名称 (R)-(+)-WIN 55212
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 90 mg/mL (172.21 mM)
    Water 90 mg/mL (172.21 mM)
    Ethanol 18 mg/mL (34.43 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.14 mL 95.68 mL 191.35 mL
    0.5 mM 3.83 mL 19.14 mL 38.27 mL
    1 mM 1.91 mL 9.57 mL 19.14 mL
    5 mM 0.38 mL 1.91 mL 3.83 mL
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