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Wiskostatin

目录号: A13903
Wiskostatin 是一种细胞渗透性的 N-烷基化咔唑衍生物,能够选择性地阻断 肌动蛋白 丝的组装。该化合物作为 N-WASP(神经性 Wiskott Aldrich 综合征蛋白)的选择性、可逆抑制剂,N-WASP 是一个信号整合蛋白。Wiskostatin 还能结合到 N-WASP,稳定其自抑制构象,并阻止 Arp2/3(与肌动蛋白相关的蛋白 2/3)复合体的激活。
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规格 价格 库存 数量
1mg
¥210.00
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5mg
¥560.00
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10mg
¥595.00
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25mg
¥1,365.00
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50mg
¥2,205.00
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100mg
¥4,060.00
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10mM * 1mL in DMSO
¥630.00
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生物活性
Discription Wiskostatin is a cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. The compound acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Wiskostatin also binds to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A13903
分子式 C17H18Br2N2O
分子量 426.15
CAS号 253449-04-6
SMILES CN(C)CC(CN1C2=C(C=C(C=C2)Br)C3=C1C=CC(=C3)Br)O
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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