WNK463

Name: WNK463
SKU: A16205

目录号: A16205

pan-WNK-kinase 抑制剂

Product Citations (1)

WNK463 Chemical Structure

CAS NO. 2012607-27-9

WNK463是口服生物可用的泛WNK激酶抑制剂。

库存：现货

规格	价格	数量
1 mg	￥ 1,100.00
5 mg	￥ 1,750.00
10 mg	￥ 2,850.00

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生物活性

WNK463是口服生物可用的泛WNK激酶抑制剂。

靶点信息

WNK-kinase

溶解度 *

In vitro (25°C)	DMSO	81 mg/mL (174.77 mM)
	Water	Insoluble
	Ethanol	81 mg/mL (174.77 mM)
In vivo	5% DMSO+30%PEG 300+5% Tween 80+ddH2O	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.58 mL	107.88 mL	215.77 mL
0.5 mM	4.32 mL	21.58 mL	43.15 mL
1 mM	2.16 mL	10.79 mL	21.58 mL
5 mM	0.43 mL	2.16 mL	4.32 mL

*The above data is based on the productmolecular weight 463.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16205
作用机制	Inhibitor (抑制剂)
M. Wt	463.46
Formula	C21H24F3N7O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2012607-27-9
Synonyms	WNK-463, WNK 463
SMILES	CC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F