WP1066

目录号: A11795

JAK 抑制剂

WP1066

WP1066 Chemical Structure

CAS NO. 857064-38-1

WP1066是一种新型的JAK2抑制剂,可抑制携带JAK2 V617F突变的类人甲状腺细胞增殖并诱导其凋亡。

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
25 mg
¥ 1,400.00
50 mg
¥ 2,100.00
10mM * 1mL in DMSO
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

WP1066是一种新型的JAK2抑制剂,可抑制携带JAK2 V617F突变的类人甲状腺细胞增殖并诱导其凋亡。
靶点信息
JAK2 (HEL cells) STAT3 (HEL cells)
2.3 μM2.43 μM
In vitro DMSO 71 mg/mL (199.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.07 mL 140.37 mL 280.74 mL
0.5 mM 5.61 mL 28.07 mL 56.15 mL
1 mM 2.81 mL 14.04 mL 28.07 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11795
作用机制 Inhibitor (抑制剂)
M. Wt 356.2
Formula C17H14BrN3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 857064-38-1
Synonyms WP 1066, WP-1066
SMILES C[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N

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