WYE-125132 (WYE-132)

Name: WYE-125132 (WYE-132)
SKU: A11038
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11038

mTOR 抑制剂

WYE-125132 是一种 ATP-竞争性 和特异性的 mTORC1 和 mTORC2 抑制剂（IC50 = 0.19 nM；对 PI3Ks 的选择性超过 5000 倍）。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥455.00	现货
10mg	¥770.00	现货
25mg	¥1,330.00	现货
50mg	¥1,925.00	现货
100mg	¥2,905.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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Data Sheet

SDS

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生物活性

Discription

WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).

Targets

Target	Value

产品信息

目录号	A11038
分子式	C27H33N7O4
分子量	519.6
CAS号	1144068-46-1
SMILES	CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7
其他名称	WYE125132, WYE-132, WYE132
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	95 mg/mL (182.83 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.25 mL	96.23 mL	192.46 mL
0.5 mM	3.85 mL	19.25 mL	38.49 mL
1 mM	1.92 mL	9.62 mL	19.25 mL
5 mM	0.38 mL	1.92 mL	3.85 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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