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NUAK kinase 抑制剂

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产品目录号: A14312


产品名 目录号 价格 数量
WZ4003 10mg A14312-10
¥ 1,000.00
WZ4003 25mg A14312-25
¥ 2,000.00
WZ4003 50mg A14312-50
¥ 3,500.00



WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14312
Mechanism of action Inhibitor
分子量 496.99
化学分子式 C25H29ClN6O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1214265-58-3
Synonyms WZ 4003, WZ-4003
化学名称 Propanamide, N-?[3-?[[5-?chloro-?2-?[[2-?methoxy-?4-?(4-?methyl-?1-?piperazinyl)?phenyl]?amino]?-?4-?pyrimidinyl]?oxy]?phenyl]?-


WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2
NUAK1 (Cell-free assay) NUAK2 (Cell-free assay)
20 nM100 nM


Solubility (25°C)* In vitro DMSO 7 mg/mL (14.08 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.12 mL 100.61 mL 201.21mL
0.5 mM 4.02 mL 20.12 mL 40.24 mL
1 mM 2.01 mL 10.06 mL 20.12 mL
5 mM 0.4 mL 2.01 mL 4.02 mL

*The above data is based on the productmolecular weight 496.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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