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WZ811

CXCR4 拮抗剂

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产品目录号: A12588

库存状态:中国现货中国现货

产品名 目录号 价格 数量
WZ811 10mg A12588-10
¥ 700.00
WZ811 25mg A12588-25
¥ 1,400.00
WZ811 50mg A12588-50
¥ 2,250.00
WZ811 100mg A12588-100
¥ 3,150.00
WZ811 10mM * 1mL in DMSO A12588-10mM-D
¥ 590.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM).

WZ811

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Chemical Information

目录号 A12588
Mechanism of action Antagonist
分子量 290.36
化学分子式 0
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 55778-02-4
Synonyms WZ811; WZ-811; WZ 811.
SMILES code C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3
化学名称 N,N'-(1,4-phenylenebis(methylene))bis(pyridin-2-amine)

生物活性

Description
WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM).
Targets
CXCR4
0.3 nM(EC50)

溶解性

Solubility (25°C)* In vitro DMSO 30 mg/mL (103.32 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.44 mL 172.2 mL 344.4mL
0.5 mM 6.89 mL 34.44 mL 68.88 mL
1 mM 3.44 mL 17.22 mL 34.44 mL
5 mM 0.69 mL 3.44 mL 6.89 mL

*The above data is based on the productmolecular weight 290.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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