Xanthohumol
目录号: A15919
COX 抑制剂
黄腺苦素，一种来自啤酒花的异戊烯基查尔酮，能够抑制COX-1和COX-2活性，并显示出化学预防效果。
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生物活性
| Discription | Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. | ||
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产品信息
| 目录号 | A15919 |
|---|---|
| 分子式 | C21H22O5 |
| 分子量 | 354.4 |
| CAS号 | 6754-58-1 |
| SMILES | CC(=CCC1=C(C=C(C(=C1O)C(=O)C=CC2=CC=C(C=C2)O)OC)O)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 67 mg/mL (189.05 mM) | |
| Water | Insoluble | ||
| Ethanol | 67 mg/mL (189.05 mM) | ||
| In vivo | 0.05% (w+w) xanthohumol powder in diet, or suspended in ethanol (2.5 mg+mL) | 12 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.22 mL | 141.08 mL | 282.17 mL |
| 0.5 mM | 5.64 mL | 28.22 mL | 56.43 mL |
| 1 mM | 2.82 mL | 14.11 mL | 28.22 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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