XL-147 (Pilaralisib)

目录号: A15283

PI3K Inhibitor

XL-147 (Pilaralisib)

XL-147 (Pilaralisib) Chemical Structure

CAS NO. 934526-89-3

XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

生物活性

XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.
Targets
PI3Kγ PI3Kβ PI3Kδ PI3Kα
23 nM36 nM36 nM39 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.48 mL 92.42 mL 184.84 mL
0.5 mM 3.7 mL 18.48 mL 36.97 mL
1 mM 1.85 mL 9.24 mL 18.48 mL
5 mM 0.37 mL 1.85 mL 3.7 mL

*The above data is based on the productmolecular weight 541.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

产品技术资料

目录号 A15283
MECHANISM OF ACTION Inhibitor
M. Wt 541.02
Formula C25H25ClN6O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 934526-89-3
Synonyms SAR245408, XL 147, XL147, SAR-245408, SAR 245408, pilaralisib
SMILES CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N

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