XL-147 (Pilaralisib)
目录号: A15283
PI3K 抑制剂
XL147是一种强效的、可口服生物利用的class I PI3K家族脂质激酶抑制剂。
Discription | XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases. | ||
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Targets |
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目录号 | A15283 |
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分子式 | C25H25ClN6O4S |
分子量 | 541.02 |
CAS号 | 934526-89-3 |
SMILES | CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N |
其他名称 | SAR245408, XL 147, XL147, SAR-245408, SAR 245408, pilaralisib |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 92 mg/mL (170.04 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 10 mM HCl in sterile water | 0.4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.48 mL | 92.42 mL | 184.84 mL |
0.5 mM | 3.7 mL | 18.48 mL | 36.97 mL |
1 mM | 1.85 mL | 9.24 mL | 18.48 mL |
5 mM | 0.37 mL | 1.85 mL | 3.7 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2