XL-888

目录号: A11251

HSP90 抑制剂

XL-888

XL-888 Chemical Structure

CAS NO. 1149705-71-4

XL888是口服可生物利用的,具有ATP竞争性的小分子热休克蛋白90(Hsp90)抑制剂,IC50为24 nM。具有潜在的抗肿瘤活性。

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 2,000.00
25 mg
¥ 4,000.00
50 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

XL888是口服可生物利用的,具有ATP竞争性的小分子热休克蛋白90(Hsp90)抑制剂,IC50为24 nM。具有潜在的抗肿瘤活性。
靶点信息
HSP90
24 nM
In vitro (25°C) DMSO 99 mg/mL (196.56 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.28 mL 198.56 mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11251
作用机制 Inhibitor (抑制剂)
M. Wt 503.63
Formula C29H37N5O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1149705-71-4
Synonyms XL888; XL-888; XL 888
SMILES CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[C@H]3CC[C@@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5

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