XL-888

目录号: A11251

HSP90 Inhibitor

XL-888 Chemical Structure

CAS NO. 1149705-71-4

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 2,000.00
25 mg
¥ 4,000.00
50 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
Targets
HSP90
24 nM
In vitro (25°C) DMSO 100 mg/mL (198.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.28 mL 198.56 mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11251
MECHANISM OF ACTION Inhibitor
M. Wt 503.63
Formula C29H37N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1149705-71-4
Synonyms XL888; XL-888; XL 888
SMILES CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[C@H]3CC[C@@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5

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