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HSP90 抑制剂

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产品目录号: A11251


产品名 目录号 价格 数量
XL-888 5mg A11251-5
¥ 1,100.00
XL-888 10mg A11251-10
¥ 2,000.00
XL-888 25mg A11251-25
¥ 4,000.00
XL-888 50mg A11251-50
¥ 7,000.00
XL-888 10mM * 1mL in DMSO A11251-10mM-D
¥ 1,700.00



XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11251
Mechanism of action Inhibitor
分子量 503.63
化学分子式 C29H37N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1149705-71-4
Synonyms XL888; XL-888; XL 888
SMILES code CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[C@H]3CC[C@@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5
化学名称 5-((R)-sec-butylamino)-N1-((1R,3s,5S)-8-(5-(cyclopropanecarbonyl)pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methylterephthalamide


XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
24 nM


Solubility (25°C) * In vitro DMSO 100 mg/mL (198.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.28 mL 198.56mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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