XL019
目录号: A12394
JAK2 抑制剂
XL019 是一种口服生物可利用的 Janus-associated kinase 2 (JAK2) 抑制剂，具有潜在的抗肿瘤活性。
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生物活性
| Discription | XL019 is an orally bioavailable inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12394 |
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| 分子式 | C25H28N6O2 |
| 分子量 | 444.53 |
| CAS号 | 945755-56-6 |
| SMILES | C1C[C@H](NC1)C(=O)NC2=CC=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5 |
| 其他名称 | XL 019, XL-019 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 14 mg/mL (31.49 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.5 mL | 112.48 mL | 224.96 mL |
| 0.5 mM | 4.5 mL | 22.5 mL | 44.99 mL |
| 1 mM | 2.25 mL | 11.25 mL | 22.5 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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