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XL184 free base (Cabozantinib)



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产品目录号: A10996


产品名 目录号 价格 数量
XL184 free base 5mg A10996-5
¥ 600.00
XL184 free base 10mg A10996-10
¥ 750.00
XL184 free base 50mg A10996-50
¥ 980.00
XL184 free base 100mg A10996-100
¥ 1,450.00
XL184 free base 10mM * 1mL in DMSO A10996-10mM-D
¥ 600.00



XL184 free base (Cabozantinib) is a small molecule designed to inhibit multiple receptor tyrosine kinases, specifically MET and VEGFR2.

XL184 free base (Cabozantinib)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 XL184 free base (Cabozantinib) 发表的文献 (1)
  • Fujita KI, .et al. Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites, J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

Chemical Information

目录号 A10996
Mechanism of action Inhibitor
分子量 501.5
化学分子式 C28H24FN3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 849217-68-1
Synonyms BMS-907351
化学名称 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide


XL184 free base (Cabozantinib) is a small molecule designed to inhibit multiple receptor tyrosine kinases, specifically MET and VEGFR2.


Solubility (25°C) * In vitro DMSO 100 mg/mL (199.39 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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