XL388

目录号: A12395

mTOR inhibitor

XL388 Chemical Structure

CAS NO. 1251156-08-7

XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR).

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,500.00
25 mg
¥ 5,000.00
100 mg
¥ 10,000.00
10mM * 1mL in DMSO
¥ 2,590.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR).
Targets
Target Value
mTORC1IC50: 8nM
mTORIC50: 9.9nM
mTORC2IC50: 166nM
PI3KαIC50: >3μM
CYP2C9IC50: 10.6μM
CYP2C8IC50: >20μM
CYP2D6IC50: >20μM
CYP3A4IC50: 24.6μM
In vitro (25°C) DMSO 23 mg/mL (50.49 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.95 mL 109.77 mL 219.54 mL
0.5 mM 4.39 mL 21.95 mL 43.91 mL
1 mM 2.2 mL 10.98 mL 21.95 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12395
MECHANISM OF ACTION Inhibitor
M. Wt 455.5
Formula C23H22FN3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1251156-08-7
Synonyms XL 388, XL-388
SMILES CC1=C(C=CC(=C1F)S(=O)(=O)C)C(=O)N2CCOC3=C(C2)C=C(C=C3)C4=CN=C(C=C4)N

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 XL388 | XL388 供应商 | 订购 XL388 | XL388 价格 | XL388 生产商 | 订单 XL388 | XL388 代理商 | 购买 1251156-08-7| 1251156-08-7 供应商 | 订购 1251156-08-7 | 1251156-08-7 价格 | 1251156-08-7 生产商 | 订单 1251156-08-7 | 1251156-08-7 代理商|buy XL388 | XL388 Supplier | purchase XL388 | XL388 cost | XL388 manufacturer | order XL388 | XL388 distributor | buy 1251156-08-7| 1251156-08-7 Supplier | purchase 1251156-08-7 | 1251156-08-7 cost | 1251156-08-7 manufacturer | order 1251156-08-7 | 1251156-08-7 distributor
Rewards