XL413
目录号: A21220
Cdc7 抑制剂
XL413 是一种强效、选择性的 Cdc7 ATP 竞争性抑制剂,其 IC50 为 3.4 nM。它还对 CK2 和 PIM1 显示出强效,IC50 分别为 215 nM 和 42 nM,以及对 pMCM 的 EC50 为 118 nM。
Discription | XL413 is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. | ||
---|---|---|---|
Targets |
|
目录号 | A21220 |
---|---|
分子式 | C14H12ClN3O2 |
分子量 | 289.72 |
CAS号 | 1169558-38-6 |
SMILES | ClC1=CC=C2C(C(N=C([C@@H]3CCCN3)NC4=O)=C4O2)=C1 |
其他名称 | XL 413, XL-413 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2