XL765

目录号: A10997

PI3K 抑制剂

XL765

XL765 Chemical Structure

CAS NO. 1349796-36-6

XL765是PI3K/mTOR双激酶抑制剂,与单独抑制PI3K激酶或mTOR激酶的药物相比,它的效力更高。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 1,670.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

XL765是PI3K/mTOR双激酶抑制剂,与单独抑制PI3K激酶或mTOR激酶的药物相比,它的效力更高。
Targets
Target Value
PI3KγIC50: 9nM
PI3KαIC50: 39nM
PI3KδIC50: 43nM
PI3KβIC50: 113nM
DNA-PKIC50: 150nM
mTORIC50: 157nM
In vitro (25°C) DMSO 10 mg/mL (16.68 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.68 mL 83.38 mL 166.75 mL
0.5 mM 3.34 mL 16.68 mL 33.35 mL
1 mM 1.67 mL 8.34 mL 16.68 mL
5 mM 0.33 mL 1.67 mL 3.34 mL

*The above data is based on the productmolecular weight 599.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10997
作用机制 Inhibitor (抑制剂)
M. Wt 599.7
Formula C31H29N5O6S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1349796-36-6
Synonyms XL-765
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC

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