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XMD 17-109

ERK5 抑制剂

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产品目录号: A14090

库存状态:中国现货中国现货

产品名 目录号 价格 数量
XMD 17-109 5mg A14090-5
¥ 1,000.00
XMD 17-109 10mg A14090-10
¥ 1,800.00
XMD 17-109 25mg A14090-25
¥ 3,350.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

XMD17-109 is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 uM in HEK293 cells.

XMD 17-109

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Chemical Information

目录号 A14090
Mechanism of action Inhibitor
分子量 638.8
化学分子式 C36H46N8O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1435488-37-1
Synonyms XMD-17-109,XMD17-109
SMILES code CCOC1=C(C=CC(=C1)C(=O)N2CCC(CC2)N3CCN(CC3)C)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C7CCCC7
化学名称 11-Cyclopentyl-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dihydro-5-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

生物活性

Description
XMD17-109 is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 uM in HEK293 cells.
Targets
ERK5
162 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.65 mL 78.27 mL 156.54mL
0.5 mM 3.13 mL 15.65 mL 31.31 mL
1 mM 1.57 mL 7.83 mL 15.65 mL
5 mM 0.31 mL 1.57 mL 3.13 mL

*The above data is based on the productmolecular weight 638.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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