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XR9576是一种 P-glycoprotein (P-gp) 抑制剂，Kd值为5.1 nM。正在研究中作为抗癌多药耐药性的佐剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.2 mL | 55.99 mL | 111.98 mL |
| 0.5 mM | 2.24 mL | 11.2 mL | 22.4 mL |
| 1 mM | 1.12 mL | 5.6 mL | 11.2 mL |
| 5 mM | 0.22 mL | 1.12 mL | 2.24 mL |
*The above data is based on the productmolecular weight 892.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13961 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 892.99 |
| Formula | C40H52N4O15S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 625375-83-9 |
| Synonyms | Tariquidar methanesulfonate hydrate |
| SMILES | COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC.CS(=O)(=O)O.CS(=O)(=O)O.O.O.O |
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