Y06137
目录号: A19656
BET 抑制剂
Y06137 是一种针对治疗去势抵抗性前列腺癌(CRPC)的强效且选择性的 BET 抑制剂。Y06137 与 BRD4(1) 溴结构域结合,其 Kd 值为 81 nM。
| Discription | Y06137 is a potent and selective BET inhibitor for treatment of castration-resistant prostate cancer (CRPC). Y06137 binds to the BRD4(1) bromodomain with a Kd of 81 nM. | |||||
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| Cell Research |
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| 目录号 | A19656 |
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| 分子式 | C27H32N4O2 |
| 分子量 | 444.57 |
| CAS号 | 2226534-49-0 |
| SMILES | CC1=NOC(C1=C2)=CC=C2C3=NC(C=C4)=C(N3CC5CCCCC5)C=C4N6CCOC[C@@H]6C |
| 其他名称 | Y 06137, Y-06137 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2