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YAP-TEAD-IN-1 TFA

目录号: A22719
YAP-TEAD-IN-1 TFA 是一种强效且具有竞争性的 YAP-TEAD 互作抑制剂(IC50=25 nM)。YAP-TEAD-IN-1 TFA 是一种17个氨基酸残基的肽,并且与 TEAD1 的结合亲和力更高(Kd=15 nM),相比之下,与 YAP (50-171) 的结合亲和力较低(Kd= 40 nM)。
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1mg
¥1,015.00
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5mg
¥2,345.00
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¥3,955.00
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Discription

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM).

产品信息
目录号 A22719
分子式 C95H145F3ClN23O23S2
分子量 2133.88
CAS号 1659305-79-9
Sequence Ac-Val-Pro-{Phe(3-Cl)}-{Hcy}-Leu-Arg-Lys-{Nle}-Pro-Ala-Ser-Phe-Cys-Lys-Pro-Pro-Glu-NH2 (Disulfide bridge:Hcy4-Cys13)
Sequence shortening Ac-VP-{Phe(3-Cl)}-{Hcy}-LRK-{Nle}-PASFCKPPE-NH2 (Disulfide bridge:Hcy4-Cys13)
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