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YM-90709

interleukin-5 receptor 拮抗剂

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产品目录号: A15999

库存状态:中国现货中国现货

产品名 目录号 价格 数量
YM-90709 5mg A15999-5
¥ 900.00
YM-90709 10mg A15999-10
¥ 1,500.00
YM-90709 50mg A15999-50
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells, with IC50 values of 1.0 and 0.57 microM, respectively.

YM-90709

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Chemical Information

目录号 A15999
Mechanism of action Antagonist
分子量 359.43
化学分子式 C22H21N3O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 163769-88-8
Synonyms YM 90709, YM90709
SMILES code CC(CC1=CC(OC)=C(OC)C=C12)(C)N3C2=CC4=NC5=CC=CC=C5N=C43
化学名称 2,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline

生物活性

Description
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells, with IC50 values of 1.0 and 0.57 microM, respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.82 mL 139.11 mL 278.22mL
0.5 mM 5.56 mL 27.82 mL 55.64 mL
1 mM 2.78 mL 13.91 mL 27.82 mL
5 mM 0.56 mL 2.78 mL 5.56 mL

*The above data is based on the productmolecular weight 359.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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