Trusted by 10,000+ Scientists since 2006



??-secretase 抑制剂

0 Customer Reviews
产品目录号: A11174


产品名 目录号 价格 数量
YO-01027 5mg A11174-5
¥ 800.00
YO-01027 10mg A11174-10
¥ 1,400.00
YO-01027 25mg A11174-25
¥ 3,200.00
YO-01027 50mg A11174-50
¥ 5,200.00
YO-01027 10mM * 1mL in DMSO A11174-10mM-D
¥ 800.00



YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11174
Mechanism of action Inhibitor
分子量 463.48
化学分子式 C26H23F2N3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 209984-56-5
Synonyms YO01027, Dibenzazepine, Deshydroxy LY 411575
SMILES code C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F
化学名称 N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide


YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.
γ secretase(APPL) (Cell-free assay) γ secretase(Notch) (Cell-free assay)
2.6 nM2.9 nM


Solubility (25°C) * In vitro DMSO 93 mg/mL (200.65 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.58 mL 107.88 mL 215.76mL
0.5 mM 4.32 mL 21.58 mL 43.15 mL
1 mM 2.16 mL 10.79 mL 21.58 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 463.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.




Keywords:购买 YO-01027 | YO-01027 供应商 | 订购 YO-01027 | YO-01027 价格 | YO-01027 生产商 | 订单 YO-01027 | YO-01027 代理商 | 购买 209984-56-5| 209984-56-5 供应商 | 订购 209984-56-5 | 209984-56-5 价格 | 209984-56-5 生产商 | 订单 209984-56-5 | 209984-56-5 代理商|buy YO-01027 | YO-01027 Supplier | purchase YO-01027 | YO-01027 cost | YO-01027 manufacturer | order YO-01027 | YO-01027 distributor | buy 209984-56-5| 209984-56-5 Supplier | purchase 209984-56-5 | 209984-56-5 cost | 209984-56-5 manufacturer | order 209984-56-5 | 209984-56-5 distributor