YO-01027

Name: YO-01027
SKU: A11174
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A11174

γ-secretase 抑制剂

1 篇发表文献

YO-01027 是一种二肽类 γ-分泌酶抑制剂，用作抗阿尔茨海默病药物。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥420.00	现货
10mg	¥805.00	现货
25mg	¥1,785.00	现货
50mg	¥3,185.00	现货
100mg	¥5,600.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用YO-01027发表的1篇文献

Weijun Zhang, .et al. , Stem Cell Rev Rep, 2023, Jan 7 PMID: 36609902

生物活性

Discription

YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.

Targets

Target	Value

产品信息

目录号	A11174
分子式	C26H23F2N3O3
分子量	463.48
CAS号	209984-56-5
SMILES	C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F
其他名称	YO01027, Dibenzazepine, Deshydroxy LY 411575
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	87 mg/mL (187.7 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% hydroxyethyl cellulose	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.58 mL	107.88 mL	215.76 mL
0.5 mM	4.32 mL	21.58 mL	43.15 mL
1 mM	2.16 mL	10.79 mL	21.58 mL
5 mM	0.43 mL	2.16 mL	4.32 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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