YO-01027

目录号: A11174

γ-secretase inhibitor

YO-01027

YO-01027 Chemical Structure

CAS NO. 209984-56-5

YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 3,200.00
50 mg
¥ 5,200.00
10mM * 1mL in DMSO
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.
Targets
γ secretase(APPL) (Cell-free assay) γ secretase(Notch) (Cell-free assay)
2.6 nM2.9 nM
In vitro (25°C) DMSO 93 mg/mL (200.65 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.58 mL 107.88 mL 215.76 mL
0.5 mM 4.32 mL 21.58 mL 43.15 mL
1 mM 2.16 mL 10.79 mL 21.58 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 463.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11174
MECHANISM OF ACTION Inhibitor
M. Wt 463.48
Formula C26H23F2N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 209984-56-5
Synonyms YO01027, Dibenzazepine, Deshydroxy LY 411575
SMILES C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F

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