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(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 57.08 mL | 285.4 mL | 570.81 mL |
| 0.5 mM | 11.42 mL | 57.08 mL | 114.16 mL |
| 1 mM | 5.71 mL | 28.54 mL | 57.08 mL |
| 5 mM | 1.14 mL | 5.71 mL | 11.42 mL |
*The above data is based on the productmolecular weight 175.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21687 |
|---|---|
| M. Wt | 175.19 |
| Formula | C8H9N5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1464851-21-5 |
| Synonyms | (Z)-Mutagenic Impurity of Tenofovir Disoproxil |
| SMILES | NC1=C2N=CN(/C=C\C)C2=NC=N1 |
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