Zearalenone
目录号: A13740
齐墩果酮是一种通常由镰刀菌属产生的植物雌激素型真菌毒素,已被证明是一种细胞毒性化合物,但也能结合到雌激素受体(ER)(IC50 值分别为 ERβ 166 nM 和 ERα 240 nM),并且在1 - 10 nM的浓度范围内,被发现能刺激这两种亚型的转录活性。
Discription | Zearalenone is a phytoestrogenic mycotoxin usually produced by Fusarium species, is shown to be a cytotoxic compound, but alos binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and was found to stimulate the transcriptional activity of both subtypes at concentrations between 1 - 10 nM. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A13740 |
---|---|
分子式 | C18H22O5 |
分子量 | 318.36 |
CAS号 | 17924-92-4 |
SMILES | C[C@H]1CCCC(=O)CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 56 mg/mL (175.9 mM) | |
Water | Insoluble | ||
Ethanol | 56 mg/mL (175.9 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 31.41 mL | 157.05 mL | 314.11 mL |
0.5 mM | 6.28 mL | 31.41 mL | 62.82 mL |
1 mM | 3.14 mL | 15.71 mL | 31.41 mL |
5 mM | 0.63 mL | 3.14 mL | 6.28 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2