Zidovudine
目录号: A15428
NRTI 抑制剂
齐多夫定是一种核苷类似物逆转录酶抑制剂（NRTI），这是一种用于治疗HIV/AIDS感染的抗逆转录病毒药物。阿滋多胸苷降低了CRISPR介导的同源定向修复（HDR）的效率。
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生物活性
| Discription | Zidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency. | |||||
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产品信息
| 目录号 | A15428 |
|---|---|
| 分子式 | C10H13N5O4 |
| 分子量 | 267.3 |
| CAS号 | 30516-87-1 |
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] |
| 其他名称 | Azidothymidine, AZT, ZDV |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 50 mg/mL (187.09 mM) | |
| Water | Warmed: 50 mg/mL (187.09 mM) | ||
| Ethanol | Warmed: 17 mg/mL (63.61 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.41 mL | 187.06 mL | 374.11 mL |
| 0.5 mM | 7.48 mL | 37.41 mL | 74.82 mL |
| 1 mM | 3.74 mL | 18.71 mL | 37.41 mL |
| 5 mM | 0.75 mL | 3.74 mL | 7.48 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 30516-87-1 | 30516-87-1 供应商 | 30516-87-1 花费 | 30516-87-1 生产商 | 订购 30516-87-1 | 30516-87-1 代理商