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Zidovudine是一种核苷类似物逆转录酶抑制剂（NRTI），是一种用于治疗HIV/AIDS感染的抗逆转录病毒药物。叠氮胸苷降低了CRISPR介导的同源性定向修复（HDR）的效率。
靶点信息
| Reverse transcriptase | ||||
| In vitro | DMSO | 50 mg/mL (187.09 mM) | |
| Water | Warmed: 50 mg/mL (187.09 mM) | ||
| Ethanol | Warmed: 17 mg/mL (63.61 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.41 mL | 187.06 mL | 374.11 mL |
| 0.5 mM | 7.48 mL | 37.41 mL | 74.82 mL |
| 1 mM | 3.74 mL | 18.71 mL | 37.41 mL |
| 5 mM | 0.75 mL | 3.74 mL | 7.48 mL |
*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15428 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 267.3 |
| Formula | C10H13N5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 30516-87-1 |
| Synonyms | Azidothymidine, AZT, ZDV |
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] |
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