ZK824190
目录号: A22591
uPA 抑制剂
ZK824190 是一种口服可用的选择性尿激酶原激活剂(uPA)抑制剂,作为多发性硬化症的潜在治疗药物。其对 uPA、tPA 和纤溶酶的 IC50 分别为 237、1600 和 1850 纳摩尔。
| Discription | ZK824190 is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively. |
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| 目录号 | A22591 |
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| 分子式 | C22H20F2N2O4 |
| 分子量 | 414.4 |
| CAS号 | 2254001-81-3 |
| SMILES | CC[C@@H](OC1=NC(OC2=CC(C3=CC=CC(CN)=C3)=CC=C2)=C(F)C=C1F)C(O)=O |
| 其他名称 | ZK 824190,ZK-824190 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2