ZM 323881 hydrochloride
目录号: A11954
VEGFR 抑制剂
ZM 323881 是一种强效且选择性的抑制剂,专门针对人类血管内皮生长因子受体 2(VEGFR2/KDR)的激酶活性。
| Discription | ZM 323881 is a potent and selective inhibitor of the kinase activity of the human vascular endothelial growth factor receptor 2 (VEGFR2/KDR). |
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| 目录号 | A11954 |
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| 分子式 | C22H18FN3O2.HCl |
| 分子量 | 411.86 |
| CAS号 | 324077-30-7 |
| SMILES | CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F.Cl |
| 其他名称 | ZM323881 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 9 mg/mL (21.85 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 1% CMC Na | 19 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.28 mL | 121.4 mL | 242.8 mL |
| 0.5 mM | 4.86 mL | 24.28 mL | 48.56 mL |
| 1 mM | 2.43 mL | 12.14 mL | 24.28 mL |
| 5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2