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ZM 336372


C-Raf 抑制剂

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产品目录号: A11077


产品名 目录号 价格 数量
ZM 336372 5mg A11077-5
¥ 400.00
ZM 336372 10mg A11077-10
¥ 700.00
ZM 336372 50mg A11077-50
¥ 2,000.00
ZM 336372 100mg A11077-100
¥ 3,500.00
ZM 336372 10mM * 1mL in DMSO A11077-10mM-D
¥ 600.00



ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.

ZM 336372




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Chemical Information

目录号 A11077
Mechanism of action Inhibitor
分子量 389.5
化学分子式 C23H23N3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 208260-29-1
Synonyms ZM-336372, ZM336372
SMILES code CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O
化学名称 3-​(dimethylamino)-​N-​[3-​[(4-​hydroxybenzoyl)amino]-​4-​methylphenyl]-​benzamide


ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.
70 nM


Solubility (25°C)* In vitro DMSO 78 mg/mL (200.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (5.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.67 mL 128.37 mL 256.74mL
0.5 mM 5.13 mL 25.67 mL 51.35 mL
1 mM 2.57 mL 12.84 mL 25.67 mL
5 mM 0.51 mL 2.57 mL 5.13 mL

*The above data is based on the productmolecular weight 389.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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