Zolbetuximab (IMAB362) is a monoclonal antibody that specifically targets Claudin-18.2, a tight junction protein predominantly expressed in certain epithelial cells. This antibody facilitates the selective eradication of Claudin-18.2-positive cells by engaging immune effector mechanisms. It is primarily utilized in scientific studies focused on gastrointestinal adenocarcinomas and pancreatic tumors, offering a critical tool for understanding and potentially targeting these malignancies.
Zolbetuximab (IMAB362) is a monoclonal antibody that specifically targets Claudin-18.2, a tight junction protein predominantly expressed in certain epithelial cells. This antibody facilitates the selective eradication of Claudin-18.2-positive cells by engaging immune effector mechanisms. It is primarily utilized in scientific studies focused on gastrointestinal adenocarcinomas and pancreatic tumors, offering a critical tool for understanding and potentially targeting these malignancies.
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