Zotarolimus
目录号: A11950
mTOR 抑制剂
Zotarolimus 是一种免疫抑制剂。它是雷帕霉素的半合成衍生物。它被设计用于搭载磷酰胆碱的支架中。
| Discription | Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. | ||
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| 目录号 | A11950 |
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| 分子式 | C52H79N5O12 |
| 分子量 | 966.21 |
| CAS号 | 221877-54-9 |
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5C=NN=N5)C)/C)O)OC)C)C)/C)OC |
| 其他名称 | A 179578, ABT 578, Resolute, 42-(1-Tetrazolyl)rapamycin |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 89 mg/mL (92.11 mM) | |
| Water | Insoluble | ||
| Ethanol | 89 mg/mL (92.11 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.35 mL | 51.75 mL | 103.5 mL |
| 0.5 mM | 2.07 mL | 10.35 mL | 20.7 mL |
| 1 mM | 1.03 mL | 5.17 mL | 10.35 mL |
| 5 mM | 0.21 mL | 1.03 mL | 2.07 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2