Zotarolimus

目录号: A11950

mTOR inhibitor

Zotarolimus Chemical Structure

CAS NO. 221877-54-9

Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier.

库存: 现货

规格 价格 数量
2 mg
¥ 1,100.00
5 mg
¥ 1,500.00
10 mg
¥ 2,400.00
25 mg
¥ 4,200.00
10mM * 1mL in DMSO
¥ 2,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier.
Targets
FKBP-12
2.8 nM
In vitro DMSO 100 mg/mL (103.49 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (103.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.35 mL 51.75 mL 103.5 mL
0.5 mM 2.07 mL 10.35 mL 20.7 mL
1 mM 1.03 mL 5.17 mL 10.35 mL
5 mM 0.21 mL 1.03 mL 2.07 mL

*The above data is based on the productmolecular weight 966.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11950
MECHANISM OF ACTION Inhibitor
M. Wt 966.21
Formula C52H79N5O12
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 221877-54-9
Synonyms A 179578, ABT 578, Resolute, 42-(1-Tetrazolyl)rapamycin
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5C=NN=N5)C)/C)O)OC)C)C)/C)OC

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