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mTOR 抑制剂

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产品目录号: A11950


产品名 目录号 价格 数量
Zotarolimus 2mg A11950-2
¥ 1,100.00
Zotarolimus 5mg A11950-5
¥ 1,500.00
Zotarolimus 10mg A11950-10
¥ 2,400.00
Zotarolimus 25mg A11950-25
¥ 4,200.00
Zotarolimus 10mM * 1mL in DMSO A11950-10mM-D
¥ 2,500.00



Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier.





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Chemical Information

目录号 A11950
Mechanism of action Inhibitor
分子量 966.21
化学分子式 C52H79N5O12
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 221877-54-9
Synonyms A 179578, ABT 578, Resolute, 42-(1-Tetrazolyl)rapamycin
SMILES code C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5C=NN=N5)C)/C)O)OC)C)C)/C)OC
化学名称 (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin


Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier.
2.8 nM


Solubility (25°C)* In vitro DMSO 100 mg/mL (103.49 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (103.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.35 mL 51.75 mL 103.5mL
0.5 mM 2.07 mL 10.35 mL 20.7 mL
1 mM 1.03 mL 5.17 mL 10.35 mL
5 mM 0.21 mL 1.03 mL 2.07 mL

*The above data is based on the productmolecular weight 966.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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