ZSTK474

目录号: A11014

PI3K inhibitor

ZSTK474 Chemical Structure

CAS NO. 475110-96-4

ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
50 mg
¥ 750.00
100 mg
¥ 1,050.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.
靶点信息
PI3Kδ (Cell-free assay) PI3Kα (Cell-free assay) PI3K (Cell-free assay) PI3Kβ (Cell-free assay) PI3Kγ (Cell-free assay)
4.6 nM16 nM37 nM44 nM49 nM
In vitro (25°C) DMSO 21 mg/mL (50.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.96 mL 119.79 mL 239.58 mL
0.5 mM 4.79 mL 23.96 mL 47.92 mL
1 mM 2.4 mL 11.98 mL 23.96 mL
5 mM 0.48 mL 2.4 mL 4.79 mL

*The above data is based on the productmolecular weight 417.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11014
MECHANISM OF ACTION Inhibitor
M. Wt 417.4
Formula C19H21F2N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 475110-96-4
Synonyms N/A
SMILES C1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5

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