AMPA receptor

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  1. PF-4778574

    Catalog No. A21157
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    AMPA receptor positive allosteric modulator
    PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models. 了解更多
  2. SYM2206

    Catalog No. A20843
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    AMPA receptor antagonist
    SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. 了解更多
  3. JNJ-61432059

    Catalog No. A20209
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    AMPAR negative modulator
    JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. 了解更多
  4. Fanapanel

    Catalog No. A21200
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    AMPA/kainate antagonist
    Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. 了解更多
  5. (S)-(-)-5-Fluorowillardiine

    Catalog No. A21337
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    AMPAR agonist
    (S)-(-)-5-Fluorowillardiine is a potent and specific AMPAR agonist. 了解更多
  6. Naspm trihydrochloride

    Catalog No. A21437
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    CP-AMPA receptors antagonist
    Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多
  7. CP 465022 hydrochloride

    Catalog No. A13321
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    AMPA 拮抗剂
    CP 465022 hydrochloride是一种选择性的非竞争性AMPA拮抗剂,在大鼠皮质神经元中的IC50为25 nM,显示出有效的抗惊厥活性。 了解更多
  8. Talampanel

    Catalog No. A15515
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    AMPA/kainate receptor 拮抗剂
    Talampanel是AMPA受体的非竞争性拮抗剂,具有抗癫痫活性。 了解更多
  9. YM90K hydrochloride

    Catalog No. A15495
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    AMPA 拮抗剂
    YM90K hydrochloride是一种选择性AMPA受体拮抗剂,在局部缺血后给药后,可延迟整体缺血模型中的神经元死亡和局部缺血模型中的脑梗塞。 了解更多
  10. Tezampanel

    Catalog No. A15259
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    AMPA 拮抗剂
    Tezampanel是AMPA和离子型谷氨酸受体的海藻酸盐家族的拮抗剂,对海藻酸盐受体的GluR5亚型具有选择性。 了解更多
  11. Fanapanel hydrate

    Catalog No. A21668
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    AMPA/kainate antagonist
    Fanapanel hydrate (ZK200775 hydrate) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. 了解更多
  12. Mibampator

    Catalog No. A21717
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    AMPA receptors potentiator
    Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors. 了解更多
  13. Philanthotoxin 74 dihydrochloride

    Catalog No. A21739
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    AMPAR antagonist
    Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. 了解更多
  14. PEPA

    Catalog No. A21904
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    AMPA receptors allosteric modulator
    PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. 了解更多
  15. CMPDA

    Catalog No. A21909
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    AMPA receptors positive allosteric modulator
    CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ?? 4.2 nM/63.4 ?? 5.6 nM for GluA2i/GluA2o receptor. 了解更多
  16. Naspm

    Catalog No. A21919
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    AMPA (CP-AMPA) receptors antagonist
    Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多
  17. CX546

    Catalog No. A21923
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    positive AMPAR modulator
    CX546 is a selective positive AMPAR modulator; the prototypical ampakine agent. 了解更多
  18. CFM-2

    Catalog No. A21930
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    non-competitive AMPAR antagonist
    CFM-2 is a selective non-competitive AMPAR antagonist. 了解更多
  19. (S)-Willardiine

    Catalog No. A21957
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    AMPA/kainate receptors agonist
    (S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM. 了解更多
  20. Becampanel

    Catalog No. A21194
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    AMPA antagonist
    Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent. 了解更多
  21. GYKI53655 Hydrochloride

    Catalog No. A17032
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    AMPA 拮抗剂
    GYKI53655 Hydrochloride是一种非竞争性AMPA和海藻酸酯受体拮抗剂。 了解更多
  22. CNQX disodium salt

    Catalog No. A16110
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    AMPA/kainate 拮抗剂
    CNQX disodium salt,AMPA/海藻酸酯拮抗剂CNQX(GLXC-11053)的水溶性形式。 了解更多
  23. CNQX

    Catalog No. A16109
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    AMPA/kainate 拮抗剂
    CNQX是一种竞争性的非NMDA谷氨酸受体拮抗剂(AMPA和海藻酸酯受体的IC50分别为0.3和1.5 uM,而NMDA受体的IC50 = 25 uM)。 了解更多
  24. Cyclothiazide

    Catalog No. A13700
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    AMPA desensitization 抑制剂
    Cyclothiazide是苯并噻二叠氮,可作为AMPA受体的增效剂,正向调节其对谷氨酸的响应(EC50 = 3.8 M)。 了解更多
  25. Farampator

    Catalog No. A13798
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    AMPA receptor modulator
    Farampator是一种AMPA受体正调节剂,它可以改善短期记忆,但会损害情景记忆。 了解更多
  26. IEM 1754 Dihydrobromide

    Catalog No. A14010
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    AMPA Receptor Blocker
    IEM 1754 Dihydrobromide是AMPA受体的电压依赖性明渠阻断剂。 了解更多
  27. DNQX

    Catalog No. A13882
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    NMDA receptor 拮抗剂
    DNQX是一种非N-甲基-D-天冬氨酸(非NMDA)受体复合物拮抗剂。 了解更多
  28. NBQX

    Catalog No. A13109
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    AMPA Receptor 拮抗剂
    NBQX是一种有效,选择性和竞争性的AMPA受体拮抗剂。 了解更多
  29. LY450108

    Catalog No. A12425
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    LY450108是一种α-氨基-3-羟基-5-甲基-4-异恶唑-丙酸(AMPA)受体增强剂。 了解更多
  30. LY404187

    Catalog No. A12424
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    LY404187是AMPA受体的选择性,有效和中枢活性的正构构调节剂。 了解更多
  31. GYKI-52466 dihydrochloride

    Catalog No. A10444
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    AMPA and Kainate 拮抗剂
    GYKI-52466 dihydrochloride是选择性非竞争性AMPA受体拮抗剂(对于AMPA、红藻氨酸和AMPA诱导的反应,IC50值分别为10-20、~ 450和> > 50 μM)。 了解更多
  32. Ampalex (CX-516)

    Catalog No. A12349
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    Ampalex (CX-516)是ampakine和nootropic,充当ampa受体阳性变构调节剂。 了解更多
  33. Aniracetam

    Catalog No. A10078
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    AMPA Receptor 抑制剂
    Aniracetam是一种安非他命,属于消旋体化学类别的促智药,据称比吡乙酰胺更有效。 了解更多

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