AZD1152-HQPA (Barasertib)

目录号: A10109

Aurora Kinase B inhibitor

AZD1152-HQPA (Barasertib) Chemical Structure

CAS NO. 722544-51-6

AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases.

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 630.00
50 mg
¥ 2,610.00
100 mg
¥ 4,680.00
10mM * 1mL in DMSO
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases.
Targets
Aurora B (Cell-free assay) Aurora A (Cell-free assay)
0.37 nM1368 nM
In vitro (25°C) DMSO 102 mg/mL (200.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (5.91 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.7 mL 98.48 mL 196.97 mL
0.5 mM 3.94 mL 19.7 mL 39.39 mL
1 mM 1.97 mL 9.85 mL 19.7 mL
5 mM 0.39 mL 1.97 mL 3.94 mL

*The above data is based on the productmolecular weight 507.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10109
MECHANISM OF ACTION Inhibitor
M. Wt 507.7
Formula C26H30FN7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 722544-51-6
Synonyms Barasertib
SMILES CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO

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