AZD1152

目录号: A15011

Aurora B inhibitor

AZD1152 Chemical Structure

CAS NO. 722543-31-9

AZD1152 is a pro-drug that rapidly undergoes phosphatase-mediated cleavage in serum to release barasertib-hQPA, a selective Aurora B kinase inhibitor that has shown preliminary activity in clinical studies of patients with acute myeloid leukemia (AML).

库存: 现货

规格 价格 数量
20 mg
¥ 3,000.00
50 mg
¥ 4,700.00
100 mg
¥ 9,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AZD1152 is a pro-drug that rapidly undergoes phosphatase-mediated cleavage in serum to release barasertib-hQPA, a selective Aurora B kinase inhibitor that has shown preliminary activity in clinical studies of patients with acute myeloid leukemia (AML).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.02 mL 85.1 mL 170.2 mL
0.5 mM 3.4 mL 17.02 mL 34.04 mL
1 mM 1.7 mL 8.51 mL 17.02 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 587.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15011
MECHANISM OF ACTION Inhibitor
M. Wt 587.54
Formula C26H31FN7O6P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 722543-31-9
Synonyms Barasertib, AZD-1152, AZD 1152
SMILES CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O

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