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|Mechanism of action||Inhibitor|
|储存方式||at -20°C 2 years|
|BKM120 (NVP-BKM120) is a bioavailable specific oral pan-class I phosphatidylinositol 3-kinase (PI3K) kinase inhibitor.|
|Solubility (25°C) *||In vitro||DMSO||82 mg/mL (199.8 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||2 mg/mL (4.87 mM)|
|In vivo||0.5% CMC Na||6 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||24.37 mL||121.83 mL||243.66mL|
|0.5 mM||4.87 mL||24.37 mL||48.73 mL|
|1 mM||2.44 mL||12.18 mL||24.37 mL|
|5 mM||0.49 mL||2.44 mL||4.87 mL|
*The above data is based on the productmolecular weight 410.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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