NVP-BKM120 Hydrochloride

目录号: A15195

PI3K 抑制剂?

NVP-BKM120 Hydrochloride

NVP-BKM120 Hydrochloride Chemical Structure

CAS NO. 1312445-63-8

NVP-BKM120 Hydrochloride是p110α/β/δ/γ的选择性PI3K抑制剂,IC50分别为52 nM/166 nM/116 nM/262 nM。对VPS34,mTOR,DNA-PK的效力降低,对PI4Kβ几乎没有活性。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 900.00
50 mg
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

NVP-BKM120 Hydrochloride是p110α/β/δ/γ的选择性PI3K抑制剂,IC50分别为52 nM/166 nM/116 nM/262 nM。对VPS34,mTOR,DNA-PK的效力降低,对PI4Kβ几乎没有活性。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.38 mL 111.89 mL 223.79 mL
0.5 mM 4.48 mL 22.38 mL 44.76 mL
1 mM 2.24 mL 11.19 mL 22.38 mL
5 mM 0.45 mL 2.24 mL 4.48 mL

*The above data is based on the productmolecular weight 446.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15195
作用机制 Inhibitor (抑制剂)
M. Wt 446.85
Formula C18H21F3N6O2.HCl
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1312445-63-8
Synonyms BKM-120 hydrochloride, BKM120 hydrochloride, BKM 120 hydrochloride
SMILES C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4.Cl

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