NVP-BKM120 Hydrochloride

目录号: A15195

PI3K Inhibitor‎

NVP-BKM120 Hydrochloride

NVP-BKM120 Hydrochloride Chemical Structure

CAS NO. 1312445-63-8

NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNA-PK, with little activity to PI4Kβ.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 900.00
50 mg
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNA-PK, with little activity to PI4Kβ.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.38 mL 111.89 mL 223.79 mL
0.5 mM 4.48 mL 22.38 mL 44.76 mL
1 mM 2.24 mL 11.19 mL 22.38 mL
5 mM 0.45 mL 2.24 mL 4.48 mL

*The above data is based on the productmolecular weight 446.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A15195
MECHANISM OF ACTION Inhibitor
M. Wt 446.85
Formula C18H21F3N6O2.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1312445-63-8
Synonyms BKM-120 hydrochloride, BKM120 hydrochloride, BKM 120 hydrochloride
SMILES C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4.Cl

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