CH5424802

目录号: A11134

ALK Inhibitor

CH5424802

CH5424802 Chemical Structure

CAS NO. 1256580-46-7

CH5424802 is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,200.00
50 mg
¥ 2,500.00
100 mg
¥ 4,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CH5424802 is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK.
Targets
Target Value
ALK(F1174L)IC50: 1nM
ALKIC50: 1.9nM
ALK(R1275Q)IC50: 3.5nM
INSRIC50: 550nM
KDRIC50: 1.4μM
AblIC50: >5μM
EGFRIC50: >5μM
FGFR2IC50: >5μM
HER2IC50: >5μM
IGF-1RIC50: >5μM
JAK1IC50: >5μM
KitIC50: >5μM
MetIC50: >5μM
PDGFRβIC50: >5μM
SrcIC50: >5μM
Akt1IC50: >5μM
Akt2IC50: >5μM
Akt3IC50: >5μM
AuroraAIC50: >5μM
CDK1IC50: >5μM
CDK2IC50: >5μM
MEK1IC50: >5μM
PKAIC50: >5μM
PKCαIC50: >5μM
PKCβ1IC50: >5μM
PKCβ2IC50: >5μM
Raf-1IC50: >5μM
In vitro (25°C) DMSO 2 mg/mL heating (4.14 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.72 mL 103.61 mL 207.21 mL
0.5 mM 4.14 mL 20.72 mL 41.44 mL
1 mM 2.07 mL 10.36 mL 20.72 mL
5 mM 0.41 mL 2.07 mL 4.14 mL

*The above data is based on the productmolecular weight 482.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11134
MECHANISM OF ACTION Inhibitor
M. Wt 482.6
Formula C30H34N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1256580-46-7
Synonyms CH-5424802
SMILES CCC1=C(C=C2C(=C1)C(=O)C3=C(C2(C)C)NC4=C3C=CC(=C4)C#N)N5CCC(CC5)N6CCOCC6

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 CH5424802 | CH5424802 供应商 | 订购 CH5424802 | CH5424802 价格 | CH5424802 生产商 | 订单 CH5424802 | CH5424802 代理商 | 购买 1256580-46-7| 1256580-46-7 供应商 | 订购 1256580-46-7 | 1256580-46-7 价格 | 1256580-46-7 生产商 | 订单 1256580-46-7 | 1256580-46-7 代理商|buy CH5424802 | CH5424802 Supplier | purchase CH5424802 | CH5424802 cost | CH5424802 manufacturer | order CH5424802 | CH5424802 distributor | buy 1256580-46-7| 1256580-46-7 Supplier | purchase 1256580-46-7 | 1256580-46-7 cost | 1256580-46-7 manufacturer | order 1256580-46-7 | 1256580-46-7 distributor
Rewards