CP-690550 (Tofacitinib citrate)

Name: CP-690550 (Tofacitinib citrate)
SKU: A10241
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A10241

JAK3 抑制剂

1 篇发表文献

CP-690550（柠檬酸托法替尼）是一种口服可用的、高度选择性的Janus激酶（JAK）家族酶的抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
50mg	¥385.00	现货
100mg	¥595.00	现货
200mg	¥840.00	现货
500mg	¥1,470.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of CP-690550 (Tofacitinib citrate)

Tofacitinib

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用CP-690550 (Tofacitinib citrate)发表的1篇文献

Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

生物活性

Discription

CP-690550 (Tofacitinib citrate) is an orally available, highly selective inhibitor of the Janus kinase (JAK) family of enzymes.

Targets

Target	Value

产品信息

目录号	A10241
分子式	C16H20N6O.C6H8O7
分子量	504.5
CAS号	540737-29-9
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 94 mg/mL (186.32 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.82 mL	99.11 mL	198.22 mL
0.5 mM	3.96 mL	19.82 mL	39.64 mL
1 mM	1.98 mL	9.91 mL	19.82 mL
5 mM	0.4 mL	1.98 mL	3.96 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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