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CYT387 sulfate salt

JAK 抑制剂

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产品目录号: A15056

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CYT387 sulfate salt 10mg A15056-10
¥ 1,050.00
CYT387 sulfate salt 50mg A15056-50
¥ 3,000.00
CYT387 sulfate salt 100mg A15056-100
¥ 5,350.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CYT387 sulfate salt is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.

CYT387 sulfate salt

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Chemical Information

目录号 A15056
Mechanism of action Inhibitor
分子量 610.62
化学分子式 C23H26N6O10S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1056636-06-6
Synonyms CYT-387 sulfate, CYT 387 sulfate, momelotinib sulfate
SMILES code C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)O
化学名称 N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide; sulfuric acid

生物活性

Description
CYT387 sulfate salt is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.38 mL 81.88 mL 163.77mL
0.5 mM 3.28 mL 16.38 mL 32.75 mL
1 mM 1.64 mL 8.19 mL 16.38 mL
5 mM 0.33 mL 1.64 mL 3.28 mL

*The above data is based on the productmolecular weight 610.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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