EGF816 (Nazartinib)

目录号: A14416

EGFR T790M 抑制剂

EGF816 (Nazartinib)

EGF816 (Nazartinib) Chemical Structure

CAS NO. 1508250-71-2

EGF816 (Nazartinib)是新型的突变选择性EGFR共价抑制剂。克服了NSCLC中T790M介导的耐药性。

库存: 现货

规格 价格 数量
5 mg
¥ 990.00
10 mg
¥ 1,680.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

EGF816 (Nazartinib)是新型的突变选择性EGFR共价抑制剂。克服了NSCLC中T790M介导的耐药性。
In vitro DMSO 92 mg/mL (185.85 mM)
Water Insoluble
Ethanol 92 mg/mL (185.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.2 mL 101.01 mL 202.01 mL
0.5 mM 4.04 mL 20.2 mL 40.4 mL
1 mM 2.02 mL 10.1 mL 20.2 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 495.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14416
作用机制 Inhibitor (抑制剂)
M. Wt 495.02
Formula C26H31ClN6O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1508250-71-2
Synonyms EGF-816, EGF 816, Nazartinib
SMILES CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl

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