Erlotinib HCl

目录号: A10362

EGFR inhibitor

Erlotinib HCl

Erlotinib HCl Chemical Structure

CAS NO. 183319-69-9

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

库存: 现货

规格 价格 数量
100 mg
¥ 400.00
250 mg
¥ 800.00
500 mg
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
Targets
HER1/EGFR (Cell-free assay)
2 nM
In vitro (25°C) DMSO 3 mg/mL (6.97 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO, 0.5% CMC Na and 15% Captisol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.26 mL 116.31 mL 232.61 mL
0.5 mM 4.65 mL 23.26 mL 46.52 mL
1 mM 2.33 mL 11.63 mL 23.26 mL
5 mM 0.47 mL 2.33 mL 4.65 mL

*The above data is based on the productmolecular weight 429.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10362
MECHANISM OF ACTION Inhibitor
M. Wt 429.9
Formula C22H23N3O4.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183319-69-9
Synonyms CP-358774, OSI-774, NSC 718781
SMILES COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl

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