|Tyr1173 (NR6W cells)||Tyr1173 (NR6wtEGFR cells)||Tyr992 (NR6wtEGFR cells)||Tyr992 (NR6W cells)|
|26 nM||37 nM||37 nM||57 nM|
|In vitro (25°C)||DMSO||89 mg/mL (199.14 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||4 mg/mL (8.95 mM)|
|In vivo||0.5% methylcellulose/0.2% Tween 80||12 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.38 mL||111.88 mL||223.76 mL|
|0.5 mM||4.48 mL||22.38 mL||44.75 mL|
|1 mM||2.24 mL||11.19 mL||22.38 mL|
|5 mM||0.45 mL||2.24 mL||4.48 mL|
*The above data is based on the productmolecular weight 446.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
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