Gemcitabine HCl (Gemzar)
Gemcitabine(Gemzar)是一种较新的化疗药物,其作用机制是在癌细胞的DNA复制过程中替换核酸的一种构建模块,从而阻止肿瘤生长。
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重要通知:仅供研究使用。我们不向患者销售。
重要通知:仅供研究使用。我们不向患者销售。
| Discription | Gemcitabine (Gemzar) is a newer chemotherapy drug acting by replacing one of the building blocks of nucleic acids during DNA replication in cancer cells, preventing tumor growth. | |||||
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| 目录号 | A10423 |
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| 分子式 | C9H11F2N3O4.HCI |
| 分子量 | 299.7 |
| CAS号 | 122111-03-9 |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.Cl |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Insoluble | |
| Water | 18 mg/mL (60.06 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | Saline | 18 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.37 mL | 166.83 mL | 333.67 mL |
| 0.5 mM | 6.67 mL | 33.37 mL | 66.73 mL |
| 1 mM | 3.34 mL | 16.68 mL | 33.37 mL |
| 5 mM | 0.67 mL | 3.34 mL | 6.67 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2