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Gemcitabine

Gemcitabine

Name: Gemcitabine
SKU: A11434

目录号: A11434

DNA synthesis inhibitor

Product Citations (1)

Gemcitabine Chemical Structure

CAS NO. 95058-81-4

Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.

库存：现货

规格	价格	数量
100 mg	￥ 450.00
500 mg	￥ 1,350.00

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生物活性

Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.

溶解度 *

In vitro (25°C)	DMSO	47 mg/mL (178.56 mM)
	Water	Warmed: 47 mg/mL (178.56 mM)
	Ethanol	Insoluble
In vivo	water (warmed)	49 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.99 mL	189.97 mL	379.94 mL
0.5 mM	7.6 mL	37.99 mL	75.99 mL
1 mM	3.8 mL	19 mL	37.99 mL
5 mM	0.76 mL	3.8 mL	7.6 mL

*The above data is based on the productmolecular weight 263.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11434
作用机制	Inhibitor (抑制剂)
M. Wt	263.2
Formula	C9H11F2N3O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	95058-81-4
Synonyms	LY 188011, LY188011, LY-188011
SMILES	O=C1N(C=CC(N)=N1)[C@H]2C(F)([C@@H]([C@H](O2)CO)O)F