HDAC6-IN-37 is an inhibitor of histone deacetylase 6 (HDAC6) with demonstrated neuroprotective effects. This compound has been shown to restore the morphology of hippocampal neurons and reduce the expression of amyloid-beta (Aβ), Tau, and phosphorylated Tau (p-Tau) proteins in the hippocampus of Alzheimer's disease (AD) model rats. Additionally, HDAC6-IN-37 inhibits the formation of senile plaques and neurofibrillary tangles while regulating oxidative stress and restoring neurotransmitter balance in brain tissue, making it a valuable tool for Alzheimer's disease research and therapeutic exploration.
HDAC6-IN-37 is an inhibitor of histone deacetylase 6 (HDAC6) with demonstrated neuroprotective effects. This compound has been shown to restore the morphology of hippocampal neurons and reduce the expression of amyloid-beta (Aβ), Tau, and phosphorylated Tau (p-Tau) proteins in the hippocampus of Alzheimer's disease (AD) model rats. Additionally, HDAC6-IN-37 inhibits the formation of senile plaques and neurofibrillary tangles while regulating oxidative stress and restoring neurotransmitter balance in brain tissue, making it a valuable tool for Alzheimer's disease research and therapeutic exploration.
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