Icotinib Hydrochloride
目录号: A13718
EGFR 抑制剂
盐酸埃克替尼是一种强效且特异性的表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI),其半抑制浓度(IC(50))为5纳摩尔,包括其EGFR突变体EGFR(L858R)、EGFR(L861Q)、EGFR(T790M)以及EGFR(T790M, L858R)。
Discription | Icotinib hydrochloride is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). | ||
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目录号 | A13718 |
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分子式 | C22H22ClN3O4 |
分子量 | 427.88 |
CAS号 | 1204313-51-8 |
SMILES | C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl |
其他名称 | BPI-2009H |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2