Icotinib

目录号: A13825

EGFR inhibitor

Icotinib

Icotinib Chemical Structure

CAS NO. 610798-31-7

Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).

库存: 现货

规格 价格 数量
5 mg
¥ 1,800.00
10 mg
¥ 2,600.00
25 mg
¥ 4,800.00
50 mg
¥ 7,800.00
10mM * 1mL in DMSO
¥ 2,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
Targets
EGFR
5 nM
In vitro (25°C) DMSO 78 mg/mL (199.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol 7 mg/mL (17.88 mM)
In vivo 0.5% CMC 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.55 mL 127.74 mL 255.48 mL
0.5 mM 5.11 mL 25.55 mL 51.1 mL
1 mM 2.55 mL 12.77 mL 25.55 mL
5 mM 0.51 mL 2.55 mL 5.11 mL

*The above data is based on the productmolecular weight 391.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A13825
MECHANISM OF ACTION Inhibitor
M. Wt 391.42
Formula C22H21N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 610798-31-7
Synonyms BPI-2009H
SMILES C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4

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