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Imatinib (Gleevec)



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产品目录号: A10259


产品名 目录号 价格 数量
Imatinib 250mg A10259-250
¥ 600.00
Imatinib 500mg A10259-500
¥ 1,100.00



Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.

Imatinib (Gleevec)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Imatinib (Gleevec) 发表的文献 (2)
  • Li Li, .et al. Evidence for activated Lck protein tyrosine kinase as the driver of proliferation in acute myeloid leukemia cell, CTV-1, Leukemia Res, 2019, 78:12-20 PMID: 30660961
  • Brittany M. Duggan, .et al. Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia, Sci Rep, 2017, 7: 1578 PMID: 28484277

Chemical Information

目录号 A10259
Mechanism of action Inhibitor
分子量 493.6
化学分子式 C29H31N7O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 152459-95-5
Synonyms STI571, Glivec
化学名称 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide


Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.
PDGFR (Cell-free assay) c-Kit (M-07e cells) v-Abl (Cell-free assay)
100 nM100 nM600 nM


Solubility (25°C)* In vitro DMSO 3 mg/mL (6.07 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.26 mL 101.3 mL 202.59mL
0.5 mM 4.05 mL 20.26 mL 40.52 mL
1 mM 2.03 mL 10.13 mL 20.26 mL
5 mM 0.41 mL 2.03 mL 4.05 mL

*The above data is based on the productmolecular weight 493.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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