Imatinib (Gleevec)

目录号: A10259

PDGFR inhibitor

Imatinib (Gleevec) Chemical Structure

CAS NO. 152459-95-5

Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.

库存: 现货

规格 价格 数量
250 mg
¥ 500.00
500 mg
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.
Targets
PDGFR (Cell-free assay) c-Kit (M-07e cells) v-Abl (Cell-free assay)
100 nM100 nM600 nM
In vitro DMSO 3 mg/mL (6.07 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.26 mL 101.3 mL 202.59 mL
0.5 mM 4.05 mL 20.26 mL 40.52 mL
1 mM 2.03 mL 10.13 mL 20.26 mL
5 mM 0.41 mL 2.03 mL 4.05 mL

*The above data is based on the productmolecular weight 493.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10259
MECHANISM OF ACTION Inhibitor
M. Wt 493.6
Formula C29H31N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 152459-95-5
Synonyms STI571, Glivec
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5

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