Imatinib Mesylate

Name: Imatinib Mesylate
SKU: A10468
Price: 210 CNY
Rating: 5 (2 reviews)

目录号: A10468

Bcr-Abl 抑制剂

2 篇发表文献

伊马替尼甲磺酸盐是一种选择性酪氨酸激酶抑制剂，通过抑制KIT信号传导途径，在治疗胃肠间质瘤中诱导了持续的客观反应。

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Grouped product items
规格	价格	库存
100mg	¥210.00	现货
200mg	¥350.00	现货
500mg	¥560.00	现货
1g	¥1,050.00	现货
5g	¥1,890.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Imatinib Mesylate

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Imatinib Mesylate发表的2篇文献

Inge Govaerts, .et al. , J Hematol Oncol, 2021, 14: 97 PMID: 34167562

Genevra Kuziel, .et al. , Cancers (Basel), 2020, Jul 28;12(8):E2083 PMID: 32731354

生物活性

Discription

Imatinib mesylate, a selective tyrosine kinase inhibitor, induced a sustained objective response in treating gastrointestinal stromal tumors with the inhibition of the KIT signal-transduction pathway.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10468
分子式	C29H31N7O.CH4SO3
分子量	589.7
CAS号	220127-57-1
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
其他名称	Gleevec, Glivec, CGP-57148B, STI-571
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	101 mg/mL (171.26 mM)
	Water	101 mg/mL (171.26 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.96 mL	84.79 mL	169.58 mL
0.5 mM	3.39 mL	16.96 mL	33.92 mL
1 mM	1.7 mL	8.48 mL	16.96 mL
5 mM	0.34 mL	1.7 mL	3.39 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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