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LDN193189 HCl

目录号: A11478
LDN193189 HCl 是 LDN193189 的盐酸盐。LDN193189 是一种高效的小分子 BMP 抑制剂,能够抑制 BMP 类型 I 受体 ALK2(IC50:5 nM)、ALK3(IC50:30 nM)和 ALK6(TGFβ1/BMP 信号传导)以及随后的 SMAD 磷酸化
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规格 价格 库存 数量
1mg
¥210.00
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2mg
¥315.00
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5mg
¥455.00
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10mg
¥560.00
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25mg
¥1,085.00
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50mg
¥1,925.00
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100mg
¥2,905.00
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10mM * 1mL in DMSO
¥630.00
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重要通知:仅供研究使用。我们不向患者销售。

Other Forms of LDN193189 HCl

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用LDN193189 HCl发表的2篇文献
  • Andreea Manole, .et al. , Cell Rep, 2023, Dec 26;42(12):113466 PMID: 38039131
  • Brandon J.Peiffer, .et al. , Cell Chem Biol, 2019, 26, 1-10 PMID: 30827938
  • 生物活性
    Discription LDN193189 HCl is the hydrochloride salt of LDN193189. LDN193189 is a highly potent small molecule BMP inhibitor that inhibits BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation.
    Targets
    Target Value
    产品信息
    目录号 A11478
    分子式 C25H22N6.HCl
    分子量 442.94
    CAS号 1062368-62-0
    SMILES C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl
    其他名称 LDN 193189
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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