LDN193189 HCl

目录号: A11478

LDN193189 HCl

LDN193189 HCl Chemical Structure

CAS NO. 1062368-62-0

LDN193189 HCl是ldn193189的盐酸盐。LDN193189是一种高效的小分子BMP抑制剂,可抑制BMP I型受体ALK2(IC50:5 nM),ALK3(IC50:30 nM)和ALK6(TGFβ1/ BMP信号转导)以及随后的SMAD磷酸化。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 900.00
25 mg
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LDN193189 HCl是ldn193189的盐酸盐。LDN193189是一种高效的小分子BMP抑制剂,可抑制BMP I型受体ALK2(IC50:5 nM),ALK3(IC50:30 nM)和ALK6(TGFβ1/ BMP信号转导)以及随后的SMAD磷酸化。
靶点信息
ALK2 (C2C12 cells) ALK3 (C2C12 cells)
5 nM30 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.58 mL 112.88 mL 225.76 mL
0.5 mM 4.52 mL 22.58 mL 45.15 mL
1 mM 2.26 mL 11.29 mL 22.58 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11478
M. Wt 442.94
Formula C25H22N6.HCl
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1062368-62-0
Synonyms LDN 193189
SMILES C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl.Cl.Cl.Cl

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