NVP-BGJ398 phosphate

目录号: A15194

FGFR Inhibitor

NVP-BGJ398 phosphate Chemical Structure

CAS NO. 1310746-10-1

NVP-BGJ398 phosphate is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 900.00
50 mg
¥ 2,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

NVP-BGJ398 phosphate is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.19 mL 75.93 mL 151.87 mL
0.5 mM 3.04 mL 15.19 mL 30.37 mL
1 mM 1.52 mL 7.59 mL 15.19 mL
5 mM 0.3 mL 1.52 mL 3.04 mL

*The above data is based on the productmolecular weight 658.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15194
MECHANISM OF ACTION Inhibitor
M. Wt 658.47
Formula C26H34Cl2N7O7P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1310746-10-1
Synonyms BGJ-398 phosphate, BGJ 398 phosphate, NVP BGJ398 phosphate
SMILES CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl.OP(=O)(O)O

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